Friday, April 25, 2008 

When It Comes to Memory, It's All About Location (HealthDay)

HealthDay - FRIDAY, April 25 (HealthDay News) -- A new report finds thatwhere protein-destroying machines reside the brain's nerve cells mayhelp determine how memories are formed, buy wholesale cinnamon p.e. finding that may play a role infuture treatments for Alzheimer's and other brain diseases.

The commercial pet food industry dmae bitartrate a multi-million dollar industry. Commercial food is most likely convenient for you, but it might be costing purchase wholesale glycocyamine nutritional supplement dog its health and you a fortune. You might even be feeding your dog a prescription diet recommended by your vet, believing you are doing the best thing.

Dogs have descended from omnivores, (flesh and vegetable eating). Our domesticated don't have the choice of hunting for their food and fossicking for particular plants and herbs Grape Seed P keep them in top shape. Your dog relies on you to do the hunting for him and to get it right.

Here's what you need to hunt for:

Protein and Amino Acids

Your dog cannot survive without protein. It can come from animal or plant sources. My preference is to base the diet on animal protein. When you feed your dog animal protein he will thrive rather than survive. Animal protein is found in good supply in any flesh - beef, chicken, turkey, fish, lamb, venison. Another good animal source is raw eggs, which should be an occasional addition to the diet. I say occasional because raw egg whites contain an enzyme that destroys biotin, a necessary nutrient in purchase wholesale ginkgo biloba leaf supplement diet. There's also a place for some yoghurt in her diet, particularly at times of special need like recovering from illness or surgery and buy wholesale creatine powder ester hcl and lactation. I'm not keen about milk because dogs lacks an enzyme which breaks down the protein in milk. Yoghurt is great because the protein has been pre-digested and your dog's digestive system will love the good bacteria in yoghurt. It's particularly good after a course of antibiotics or surgery, to replace the intestinal flora.

So, your best hunting will bring back:

  • meats, the offal meats heart, spleen and liver are particularly nutrient rich

  • eggs

  • yoghurt

Very few commercial dog foods list protein as the first glycine wholesale shipping to canada and australia and never do they tell you the source of the protein. I'm not going to go there, it's horrible.

If you're feeding your dog a diet based exclusively on plant protein you'll need to be sure he's getting the 10 purchase wholesale grapeseed powder extracts amino acids that he cannot make in his gut. The other tricky thing about using plant sources for protein is that you can exceed the calorie (kilojoule) requirements very easily which will make him fat not fit. This is one of the problems with commercial dry foods based on grain products as most are.

Plant sources of protein are:

  • grains like rice, barley, corn, wheat, soybeans and oatmeal

  • nuts and seeds

  • legumes

  • vegetables

  • fruits

Plant sources of protein will provide other nutrients - vitamins, minerals, fatty acids, and fiber, so it's good to include these. I discuss their importance and place in the next article.

As a guide, a normal adult dog should get at least 10% of their total calories from protein. Older dogs will often need more, as will pregnant and lactating bitches.

That's the protein bit of the hunt covered. You'll find what to forage for next in the second part of this article where I share some of the scary truths about additives in commercial dog foods and where you'll get the info you need about Fats and Fatty Acids, Minerals and Vitamins and Energy Needs.

Learn how you can give your dog a long, happy, healthy life. Discover little known secrets in my free report Seven Veterinary Secrets Revealed. http://www.dog-health-solution.com/index.html During my lifetime of caring for pets, I've done a lot of searching for ways to heal my sick animals. When veterinary medicine didn't have answers for me, I went looking for alternatives. I'm a complementary health-care professional, so it seemed the obvious way to go. Ease the heartache, expense and frustration of seeing your dog get sicker as you hand over more and more money to the vet. http://www.dog-health-solution.com/index.html

 

Senate passes genetic discrimination bill (AP)

AP - People learning through genetic testing that they might be susceptible to devastating diseases wouldn't also have to worry about losing their jobs or their health insurance under anti-discrimination legislation the Senate 1kg 1.5kg 5kg 500g 750g gram kilo kilogram 250g 75g 50g 25g Thursday.

In a 2006 article in Biological & Pharmaceutical Bulletin, Naganuma et.al. write that both turmeric curcumin edta calcium disodium certain reactions in cultured cells that indicate the anti-cancer effects of turmeric and curcumin may at least be partly due to how they affect what is known as conjugation in the body.

Conjugation is a critical point

When body ingests something, such as a drug or chemical, it undergoes various reactions in your body. It can have certain molecules added to it which help the body eliminate the drug or chemical via the urinary system, or it can be detoxified, or it can undergo a reaction which makes it dangerous to the body. The last kind of reaction can turn a pro-carcinogen into a carcinogen.

The Green Tea Pe 98 (40 Egcg) 250g name for certain groups of these reactions is conjugation. Conjugation reactions which have been considered important in how procarcinogens are handled by the body include glucuronidation and sulfo-conjugation. These reactions in the body change bioactivate a procarcinogen. Inhibition of these reactions may help with anti-cancer treatment.

Study shows turmeric and curcumin modulate conjugation

The researchers of the study chose to use a known pro-carcinogen, 1-Napthol, as a model. They used cultured Human colonic adenocarcinoma cells, known as Caco-2 cells. These cells are used as tools for studying intestinal cell function.

The work concludes that both curcumin and turmeric strongly inhibit sulfoconjugation. Since curcumin alone achieved the same levels of inhibition, they conclude that the curcumin activity may largely be responsible for this effect.

The levels of glucuronidation of 1-Napthol were different for turmeric and curcumin, however. The turmeric effect buy wholesale glucosamine hcl actually larger than the curcumin effect, possibly suggesting that turmeric contains buy wholesale beta-alanine online ingredients besides curcumin that help inhibit glucuronidation. This could be interesting news, as it implies that the natural spice could do as well if not better in helping the body's natural detoxification system than the purified curcumin.

The research studied to the level of gene expression the effects of curcumin and natural coffee extract bulk caffeine Other studies have also claimed that turmeric and curcumin can affect the way drugs or chemicals are handled by the body by regulating how they affect gene expression.

This means that not only the biochemical activity of curcumin as an anti-oxidant could be the source of the chemoprotective activity of curcumin and turmeric. It could be that curcumin and turmeric actually affect how the body's natural genetic defenses are rallied.

That's the good news, now the bad news

There are serious experimental design problems with this research work as reported. The most glaring problem is a lack of reported data for a control on the DMSO (dimethyl sulfoxide) used to dissolve the curcumin and turmeric. DMSO is itself a very bioactive molecule. DMSO in its own time was examined for many potential health effects, both beneficial and negative.

Perhaps the reviewers of the article had access to more data which was not shown in the published article. If so, it should have been mentioned in the text whether a DMSO only sample was examined.

Another problem is the concentration claimed for the curcumin and turmeric in the materials and methods. An attempt to repeat the stock of 10 grams of turmeric in either 100 ml distilled water or DMSO showed that turmeric is largely left as a sludge at this concentration. It is almost impossible to filter the turmeric in water solution at this concentration.

Where does that leave us?

The results of this study are very interesting, and would need to be investigated more thoroughly and with proper controls. The effects on the conjugation system were definitely observed, we just lack proof that it was indeed curcumin and turmeric which caused the effects.

One of the most interesting aspects of this study is that in comparing the naturally occurring turmeric with the purified curcumin, at least one system seems to react stronger to turmeric. Around the world, interest in curcumin was aroused due to the fact that populations which ingest large amounts of turmeric have lower incidences of certain diseases. The scientific community always prefers to narrow down active biochemicals in plants and try to characterize them.

However, nature often bioactive molecules with other beneficial molecules which are not easily defined at first in the laboratory. This study should be the basis of a scientific inquiry into the benefits of whole powdered turmeric. As a treatment, it would be far cheaper than the purified curcumin. If the health benefits exist after cooking, then simply adapting ethnic cuisines heavily using turmeric could be a natural chemopreventive recommendation.

Sources: Biol Pharm Bull. 2006 Jul;29(7):1476-9. Turmeric and curcumin modulate the conjugation of 1-naphthol in Caco-2 cells. Naganuma M, Saruwatari canadian nutritional supplements Okamura S, Tamura H.

Samantha Rangen writes about home health issues. She has a BA in chemistry and has worked as a research technician for over 20 years in biochemistry, genetics, biochemistry, and cancer research.

Samantha markets discount home medical equipment, including canes at http://www.getinspec.com